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Molecular analysis of sermorelin's mechanism as a growth hormone-releasing hormone analogue. Investigates GHRH receptor binding, pituitary gland stimulation, and pulsatile growth hormone release patterns in experimental models.

Sermorelin
GHRH
Growth Hormone

Receptor pharmacology study characterizing melanotan II binding to melanocortin receptors (MC1R, MC3R, MC4R). Analyzes receptor selectivity, signal transduction pathways, and downstream effects in transfected cell expression systems.

Melanotan II
Melanocortin Receptor
MC4R

Cellular biology investigation of epithalon's effects on telomerase activation and potential anti-senescence mechanisms. Examines telomere length maintenance, cell cycle regulation, and longevity-related pathways in cultured cell models.

Epithalon
Telomerase
Cellular Senescence

Comparative study of GHRP-2 and GHRP-6 mechanisms in stimulating growth hormone release through ghrelin receptor pathways. Analyzes potency differences, receptor binding affinities, and downstream signaling cascades in vitro and in vivo models.

GHRP-2
GHRP-6
Growth Hormone Release

Characterization of ipamorelin's selective ghrelin receptor (GHS-R1a) agonism without affecting cortisol, prolactin, or ACTH. Examines growth hormone pulse amplification and metabolic effects in laboratory research settings.

Ipamorelin
Ghrelin Receptor
Growth Hormone

Neuropharmacological study of selank's anxiolytic-like properties in behavioral models. Investigates GABAergic system modulation, monoamine neurotransmitter effects, and stress response regulation in laboratory neurochemistry research.

Selank
Anxiolytic
GABAergic

Neuropharmacological study of PT-141's selective MC4R agonism in central nervous system pathways. Investigates neural activation patterns, receptor distribution, and signal transduction in brain slice preparations and cellular models.

PT-141
Bremelanotide
MC4R

Structural analysis of modified GRF 1-29 (Mod GRF) examining amino acid substitutions enhancing stability and potency. Investigates GHRH receptor binding dynamics and resistance to enzymatic degradation in biochemical assays.

Mod GRF 1-29
Structure-Activity
GHRH Receptor

Clinical review examining thymosin beta-4 (TB-500) applications in tissue repair and regeneration. Explores actin-sequestering properties, cell migration enhancement, and anti-inflammatory effects in wound healing and cardiovascular repair models.

TB-500
Thymosin Beta-4
Tissue Repair

Comprehensive review of BPC-157's wound healing applications including skin wounds, deep burns, diabetic ulcers, and alkali burns. Examines cytoprotective mechanisms, angiomodulatory effects, and practical applicability across multiple tissue types with no reported toxicity.

BPC-157
Wound Healing
Cytoprotection

Foundational research examining BPC-157's therapeutic potential in hypovascular and hypocellular soft tissues including tendons and ligaments. Demonstrates beneficial effects in skeletal muscle injury models from both direct trauma and systemic insults.

BPC-157
Tendon
Ligament

Molecular study demonstrating BPC-157 dose- and time-dependently increases growth hormone receptor expression in tendon fibroblasts at both mRNA and protein levels. Reveals growth hormone activation of JAK-STAT signaling pathway in BPC-157-treated cells.

BPC-157
Growth Hormone Receptor
JAK-STAT
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