⚠️ RESEARCH USE ONLY - NOT FOR HUMAN CONSUMPTION - NOT APPROVED BY MHRA - 18+ ONLY

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MOTS-c Research & Scientific Studies

Explore the latest peer-reviewed research and scientific studies

About MOTS-c

MOTS-c is a 16-amino acid mitochondrial-derived peptide studied in metabolic research. Supplied as a lyophilized powder for laboratory investigations into mitochondrial function, metabolic signaling pathways, and cellular stress-response mechanisms in controlled experimental models. Each batch undergoes analytical verification for identity and purity using HPLC and mass spectrometry. Supplied as: Lyophilized powder Purity: >95-99 (HPLC verified) Storage: Store desiccated at ?20�C for long-term. Short-term room temperature exposure (around 1 month) during shipping/handling is generally acceptable if kept sealed, dry, and protected from heat/light. Designation: FOR RESEARCH USE ONLY. Not intended for human or animal consumption.

Purity>95-99
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Latest Research

Featured Study

Mitochondria-derived peptide hydrogel augments mitochondrial transplantation for promoting cardiac repair via macrophage metabolic reprogramming.

Li H et al.•Bioact Mater•2027

Recent research on MOTS-c: Mitochondria-derived peptide hydrogel augments mitochondrial transplantation for promoting cardiac repair via macrophage metabolic reprogramming.

Read Full Study on PubMed
Featured Study

MOTS-c in sepsis-induced cardiomyopathy: Mechanisms and translational potential.

Zhao Z et al.•Eur J Pharmacol•2026

Recent research on MOTS-c: MOTS-c in sepsis-induced cardiomyopathy: Mechanisms and translational potential.

Read Full Study on PubMed

Additional Studies

Mitokines as bioenergetic stress signals in cardiovascular disease: mitochondrial communication, endocrine adaptation, and translational implications.

Kurian GA et al.•J Bioenerg Biomembr•2026

Recent research on MOTS-c: Mitokines as bioenergetic stress signals in cardiovascular disease: mitochondrial communication, endocrine adaptation, and translational implications.

Read on PubMed

Correction: Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction.

Kutuk IS et al.•Sci Rep•2026

Recent research on MOTS-c: Correction: Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction.

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Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders: A systematic review.

Ayubi N et al.•Physiol Int•2026

Recent research on MOTS-c: Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders: A systematic review.

Read on PubMed

MOTS-c is a mitochondrial-encoded interferon-linked host defense peptide.

Rice MC et al.•Elife•2026

Recent research on MOTS-c: MOTS-c is a mitochondrial-encoded interferon-linked host defense peptide.

Read on PubMed

Emerging regulators of human physiology and disease; sORF-encoded microproteins.

Mustafa AM et al.•Epigenomics•2026

Recent research on MOTS-c: Emerging regulators of human physiology and disease; sORF-encoded microproteins.

Read on PubMed

Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.

Horwath O et al.•Exp Physiol•2026

Recent research on MOTS-c: Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.

Read on PubMed

Related Research

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Research Disclaimer

The research articles and studies referenced on this page are for informational purposes only. All products are sold for research use only and are not intended for human or animal consumption. The information provided does not constitute medical advice, diagnosis, or treatment. Always consult with qualified healthcare professionals before making any decisions related to health or medical treatment.