⚠️ RESEARCH USE ONLY - NOT FOR HUMAN CONSUMPTION - NOT APPROVED BY MHRA - 18+ ONLY

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MOTS-c Research & Scientific Studies

Explore the latest peer-reviewed research and scientific studies

About MOTS-c

MOTS-c is a 16-amino acid mitochondrial-derived peptide studied in metabolic research. Supplied as a lyophilized powder for laboratory investigations into mitochondrial function, metabolic signaling pathways, and cellular stress-response mechanisms in controlled experimental models. Each batch undergoes analytical verification for identity and purity using HPLC and mass spectrometry. Supplied as: Lyophilized powder Purity: >95-99 (HPLC verified) Storage: Store desiccated at ?20�C for long-term. Short-term room temperature exposure (around 1 month) during shipping/handling is generally acceptable if kept sealed, dry, and protected from heat/light. Designation: FOR RESEARCH USE ONLY. Not intended for human or animal consumption.

Purity>95-99
Categorypeptide

Latest Research

Featured Study

Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?

Filibeli BE et al.Arch Endocrinol Metab2026

Recent research on MOTS-c: Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?

Read Full Study on PubMed
Featured Study

Mitochondrial-derived peptide MOTS-c targets SLC7A11 to preserve spermatogenesis by suppressing ferroptosis.

Liu S et al.Free Radic Biol Med2026

Recent research on MOTS-c: Mitochondrial-derived peptide MOTS-c targets SLC7A11 to preserve spermatogenesis by suppressing ferroptosis.

Read Full Study on PubMed

Additional Studies

Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway.

Chen D et al.Eur J Pharmacol2026

Recent research on MOTS-c: Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway.

Read on PubMed

Effects of graviola oil extract on fattening performance and circadian rhythms of adipokine, cardiac and mitochondrial function markers in lambs.

Kotan GC et al.BMC Vet Res2026

Recent research on MOTS-c: Effects of graviola oil extract on fattening performance and circadian rhythms of adipokine, cardiac and mitochondrial function markers in lambs.

Read on PubMed

Mitochondrial-derived microproteins in lung disease: insights and implications.

Behan M et al.Am J Physiol Lung Cell Mol Physiol2026

Recent research on MOTS-c: Mitochondrial-derived microproteins in lung disease: insights and implications.

Read on PubMed

MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling Pathway.

Li N et al.Protein Pept Lett2026

Recent research on MOTS-c: MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling Pathway.

Read on PubMed

Therapeutic Effects of MOTS-c in the Valproic Acid-Induced Autism Model in Rats: Role of Tetrahydrobiopterin and Brain-Derived Neurotrophic Factor.

Güvenir Seven S et al.Mol Neurobiol2026

Recent research on MOTS-c: Therapeutic Effects of MOTS-c in the Valproic Acid-Induced Autism Model in Rats: Role of Tetrahydrobiopterin and Brain-Derived Neurotrophic Factor.

Read on PubMed

Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction.

Kutuk IS et al.Sci Rep2026

Recent research on MOTS-c: Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction.

Read on PubMed

Related Research

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Research Disclaimer

The research articles and studies referenced on this page are for informational purposes only. All products are sold for research use only and are not intended for human or animal consumption. The information provided does not constitute medical advice, diagnosis, or treatment. Always consult with qualified healthcare professionals before making any decisions related to health or medical treatment.