Verified Peptides

LL-37 Research & Scientific Studies

Explore the latest peer-reviewed research and scientific studies

About LL-37

LL-37 is the only human cathelicidin antimicrobial peptide and is widely used in immunology and innate-immunity research. Supplied as a lyophilized powder for laboratory investigations into innate immune signaling, host-defense pathway markers, and immunomodulatory mechanisms in controlled experimental models. Each batch is verified for identity and purity using HPLC and mass spectrometry. Supplied as: Lyophilized powder Purity: >95-99 (HPLC verified) Storage: Store desiccated at ?20�C for long-term. Short-term room temperature exposure (around 1 month) during shipping/handling is generally acceptable if kept sealed, dry, and protected from heat/light. Designation: FOR RESEARCH USE ONLY. Not intended for human or animal consumption.

Purity>95-99
Categorypeptide

Latest Research

Featured Study

Microbiota modulation by a human Paneth cell α-defensin fragment protects against DSS-induced colitis.

Bonazzi E et al.iScience2026

Recent research on LL-37: Microbiota modulation by a human Paneth cell α-defensin fragment protects against DSS-induced colitis.

Read Full Study on PubMed
Featured Study

SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting.

Zhang Y et al.Proc Natl Acad Sci U S A2026

Recent research on LL-37: SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting.

Read Full Study on PubMed

Additional Studies

Immunomodulatory effects of cathelicidin in the gut-brain axis: A novel link between mucosal immunity and neuroinflammation.

Nourizadeh M et al.Exp Physiol2026

Recent research on LL-37: Immunomodulatory effects of cathelicidin in the gut-brain axis: A novel link between mucosal immunity and neuroinflammation.

Read on PubMed

LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.

Asmamaw D et al.Eur J Med Chem2025

Recent research on LL-37: LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.

Read on PubMed

CXCL2-TLR4 axis activates NETs by accelerating autophagy through ATG7 to promote the progression of idiopathic interstitial pneumonia.

He J et al.Mol Immunol2025

Recent research on LL-37: CXCL2-TLR4 axis activates NETs by accelerating autophagy through ATG7 to promote the progression of idiopathic interstitial pneumonia.

Read on PubMed

Extended-Spectrum β-Lactamase-Producing Escherichia coli and Pediatric UTIs: A Review of the Literature and Selected Experimental Observations.

Tamas V et al.Antibiotics (Basel)2025

Recent research on LL-37: Extended-Spectrum β-Lactamase-Producing Escherichia coli and Pediatric UTIs: A Review of the Literature and Selected Experimental Observations.

Read on PubMed

Differences in Inflammatory Genetic Profiles in Periodontitis Associated with Genetic and Immunological Disorders: A Systematic Review.

Astolfi-Labrador L et al.Biomedicines2025

Recent research on LL-37: Differences in Inflammatory Genetic Profiles in Periodontitis Associated with Genetic and Immunological Disorders: A Systematic Review.

Read on PubMed

LL-37 as a biomarker for therapeutic response to scaling and root planing.

Rao KS et al.J Indian Soc Periodontol2025

Recent research on LL-37: LL-37 as a biomarker for therapeutic response to scaling and root planing.

Read on PubMed

Related Research

Purchase LL-37 from Verified Peptides

High-purity research peptides with full analytical verification

  • 99% Purity (HPLC Verified)
  • Full Certificate of Analysis
  • Same Day Dispatch
  • Free UK Shipping Over £75
Buy LL-37 - 99% Purity, Same Day Dispatch

Research Disclaimer

The research articles and studies referenced on this page are for informational purposes only. All products are sold for research use only and are not intended for human or animal consumption. The information provided does not constitute medical advice, diagnosis, or treatment. Always consult with qualified healthcare professionals before making any decisions related to health or medical treatment.