⚠️ RESEARCH USE ONLY - NOT FOR HUMAN CONSUMPTION - NOT APPROVED BY MHRA - 18+ ONLY

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FOXO4-DRI Research & Scientific Studies

Explore the latest peer-reviewed research and scientific studies

About FOXO4-DRI

FOXO4-DRI (FOXO4 D-Retro-Inverso) is a synthetic peptide used in aging and cellular-regulation research investigating FOXO4�p53 interaction and senescence-associated pathway markers. Supplied as a lyophilized powder for laboratory studies of cellular stress-response signaling in controlled experimental models. Each batch undergoes analytical verification for identity and purity using HPLC and mass spectrometry. Supplied as: Lyophilized powder Purity: 99%+ (HPLC verified) Storage: Store desiccated at ?20�C for long-term. Short-term room temperature exposure (around 1 month) during shipping/handling is generally acceptable if kept sealed, dry, and protected from heat/light. Designation: FOR RESEARCH USE ONLY. Not intended for human or animal consumption.

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Latest Research

Featured Study

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Bourgeois B et al.Nat Commun2025

Recent research on FOXO4-DRI: The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Read Full Study on PubMed
Featured Study

FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation.

Kong YX et al.Commun Biol2025

Recent research on FOXO4-DRI: FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation.

Read Full Study on PubMed

Additional Studies

FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway.

Hu Z et al.Front Bioeng Biotechnol2025

Recent research on FOXO4-DRI: FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway.

Read on PubMed

FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells.

Li Y et al.Exp Gerontol2024

Recent research on FOXO4-DRI: FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells.

Read on PubMed

Cellular Senescence Contributes to the Progression of Hyperoxic Bronchopulmonary Dysplasia.

Jing X et al.Am J Respir Cell Mol Biol2024

Recent research on FOXO4-DRI: Cellular Senescence Contributes to the Progression of Hyperoxic Bronchopulmonary Dysplasia.

Read on PubMed

Related Research

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Research Disclaimer

The research articles and studies referenced on this page are for informational purposes only. All products are sold for research use only and are not intended for human or animal consumption. The information provided does not constitute medical advice, diagnosis, or treatment. Always consult with qualified healthcare professionals before making any decisions related to health or medical treatment.